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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GNMT
All Species:
32.73
Human Site:
Y196
Identified Species:
72
UniProt:
Q14749
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14749
NP_061833.1
295
32742
Y196
A
P
P
G
K
N
I
Y
Y
K
S
D
L
T
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001089876
295
32693
Y196
A
P
P
G
K
N
I
Y
Y
K
S
D
L
T
K
Dog
Lupus familis
XP_532140
295
32695
Y196
A
P
P
G
K
N
I
Y
Y
K
S
D
L
T
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXF8
293
32657
Y194
A
P
P
G
K
N
I
Y
Y
K
S
D
L
T
K
Rat
Rattus norvegicus
P13255
293
32531
Y194
A
P
P
G
K
N
I
Y
Y
K
S
D
L
T
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508790
588
65253
Y489
A
P
P
G
K
N
I
Y
Y
K
S
D
L
T
K
Chicken
Gallus gallus
XP_001232829
531
58160
Y432
A
P
P
G
K
N
I
Y
Y
K
S
D
L
T
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_997981
294
33227
Y195
V
P
Q
G
K
N
I
Y
Y
K
S
D
L
K
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650223
289
32665
A191
D
N
I
L
E
T
G
A
T
P
A
K
S
I
Y
Honey Bee
Apis mellifera
XP_625210
292
33740
Y194
N
I
P
S
K
C
I
Y
Y
N
S
Q
H
M
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784229
290
32784
N192
H
G
I
A
V
N
K
N
I
Y
H
K
V
D
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.6
96.2
N.A.
91.8
91.5
N.A.
39.6
38.9
N.A.
72.5
N.A.
56.9
57.9
N.A.
36.6
Protein Similarity:
100
N.A.
99.6
97.2
N.A.
95.5
95.9
N.A.
45.2
47
N.A.
83.3
N.A.
72.1
72.1
N.A.
53.2
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
100
N.A.
73.3
N.A.
0
40
N.A.
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
100
N.A.
80
N.A.
13.3
40
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
64
0
0
10
0
0
0
10
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
0
0
0
73
0
10
0
% D
% Glu:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
73
0
0
10
0
0
0
0
0
0
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% H
% Ile:
0
10
19
0
0
0
82
0
10
0
0
0
0
10
10
% I
% Lys:
0
0
0
0
82
0
10
0
0
73
0
19
0
10
64
% K
% Leu:
0
0
0
10
0
0
0
0
0
0
0
0
73
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
10
10
0
0
0
82
0
10
0
10
0
0
0
0
0
% N
% Pro:
0
73
73
0
0
0
0
0
0
10
0
0
0
0
0
% P
% Gln:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
10
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
10
0
0
0
0
0
0
82
0
10
0
0
% S
% Thr:
0
0
0
0
0
10
0
0
10
0
0
0
0
64
10
% T
% Val:
10
0
0
0
10
0
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
82
82
10
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _